{"product_id":"e2f1-antibody-abccs46940","title":"E2F1 Antibody","description":"\u003ch4\u003eSize\u003c\/h4\u003e\u003cp\u003e100ug\u003c\/p\u003e\u003ch4\u003eClone Number\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eAliases\u003c\/h4\u003e\u003cp\u003eDmel\\CG6376 antibody; Dmel_CG6376 antibody; drosE2F1 antibody; E(Sev-CycE)3A antibody; E(var)3-93E antibody; E2-promoter binding facto antibody; E2F 1 antibody; E2F transcription factor 1 antibody; E2F-1 antibody; E2f-PA antibody; E2f-PB antibody; E2f-PC antibody; E2F1 antibody; E2f1 E2F transcription factor 1 antibody; E2F1_HUMAN antibody; Evar(3)164 antibody; KIAA4009 antibody; l(3)07172 antibody; l(3)j3B1 antibody; l(3)j3C2 antibody; l(3)rM729 antibody; mKIAA4009 antibody; OTTHUMP00000030661 antibody; PBR3 antibody; PRB binding protein E2F 1 antibody; PRB-binding protein E2F-1 antibody; RBAP 1 antibody; RBAP-1 antibody; RBAP1 antibody; RBBP-3 antibody; RBBP3 antibody; RBP 3 antibody; RBP3 antibody; Retinoblastoma-associated protein 1 antibody; Retinoblastoma-binding protein 3 antibody; Transcription factor E2F1 antibody\u003c\/p\u003e\u003ch4\u003eImmunogen Species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eUniProt ID\u003c\/h4\u003e\u003cp\u003eQ01094\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eRecombinant Human Transcription factor E2F1 protein (133-362AA)\u003c\/p\u003e\u003ch4\u003eRaised in\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eSpecies Reactivity\u003c\/h4\u003e\u003cp\u003eHuman, Mouse\u003c\/p\u003e\u003ch4\u003eTested Applications\u003c\/h4\u003e\u003cp\u003eELISA, WB, IHC, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IP:1:200-1:2000\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5\\\\\\'-TTTC[CG]CGC-3\\\\\\' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1\/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53\/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812).\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003ePurification Method\u003c\/h4\u003e\u003cp\u003e\u0026gt;95%, Protein G purified\u003c\/p\u003e\u003ch4\u003eConjugate\u003c\/h4\u003e\u003cp\u003eNon-conjugated\u003c\/p\u003e\u003ch4\u003eBuffer\u003c\/h4\u003e\u003cp\u003ePreservative: 0.03% Proclin 300\u003cbr\u003eConstituents: 50% Glycerol, 0.01M PBS, PH 7.4\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eLiquid\u003c\/p\u003e\u003ch4\u003eStroage\u003c\/h4\u003e\u003cp\u003eUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.\u003c\/p\u003e\u003ch4\u003eTarget Names\u003c\/h4\u003e\u003cp\u003eE2F1\u003c\/p\u003e\u003ch4\u003eResearch Areas\u003c\/h4\u003e\u003cp\u003eEpigenetics and Nuclear Signaling; Cancer\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"Default Title","offer_id":42344496627946,"sku":"ABCCS46940","price":350210.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_13c34399-f856-4258-9a35-ba15ef91c922.png?v=1650904151","url":"https:\/\/danabiosci.com\/products\/e2f1-antibody-abccs46940","provider":"Dana Bioscience","version":"1.0","type":"link"}