{"product_id":"collagen-i-alpha-1-cleaved-ala1218-rabbit-polyclonal-antibody-abcb07266","title":"Collagen I alpha 1 (Cleaved-Ala1218) Rabbit Polyclonal Antibody","description":"\u003ch4\u003eAb type\u003c\/h4\u003e\u003cp\u003ePrimary antibody\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eThis gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone| cornea| dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV| Ehlers-Danlos syndrome type VIIA| Ehlers-Danlos syndrome Classical type| Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22| where this gene and the gene for platelet-derived growth factor beta are located| are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans| resulting from unregulated expression of the growth factor. Two transcripts| resulting from the use of alternate polyadenylation signals| have been identified for this gene. \u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Mouse, Rat\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eSynthesized peptide derived from human Collagen I α1 (Cleaved-Ala1218)\u003c\/p\u003e\u003ch4\u003eStorage Stability\u003c\/h4\u003e\u003cp\u003e-20°C for 1 year\u003c\/p\u003e\u003ch4\u003eConcentration\u003c\/h4\u003e\u003cp\u003e1 mg\/ml\u003c\/p\u003e\u003ch4\u003eMolecularWeight_Da\u003c\/h4\u003e\u003cp\u003e161040\u003c\/p\u003e\u003ch4\u003esynonyms\u003c\/h4\u003e\u003cp\u003eCollagen I α1 ;Cleaved-Ala1218; Collagen alpha-1;I chain; Alpha-1 type I collagen\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42404525113578,"sku":"ABCB07266","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_839ce867-cdf1-4fa4-858a-2d66b7ab8a5e.png?v=1645223190","url":"https:\/\/danabiosci.com\/products\/collagen-i-alpha-1-cleaved-ala1218-rabbit-polyclonal-antibody-abcb07266","provider":"Dana Bioscience","version":"1.0","type":"link"}