{"product_id":"anti-rspo2-antibody-abcf07349","title":"anti- RSPO2 antibody","description":"\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eUniprot ID\u003c\/h4\u003e\u003cp\u003eQ6UXX9\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eliquid\u003c\/p\u003e\u003ch4\u003ePurification\u003c\/h4\u003e\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\u003ch4\u003ePurity\u003c\/h4\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e\n\u0026gt;= 95%\u003c\/p\u003e as determined by SDS-PAGE\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003epolyclonal\u003c\/p\u003e\u003ch4\u003eClone ID\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eStorage\u003c\/h4\u003e\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eActivator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt\/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eR-spondin 2 homolog\u003c\/p\u003e\u003ch4\u003eSynonyms\u003c\/h4\u003e\u003cp\u003eCRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 \u003c\/p\u003e\u003ch4\u003eObserved MW\u003c\/h4\u003e\u003cp\u003e33 kDa\u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Mouse, Rat\u003c\/p\u003e\u003ch4\u003eTested Application\u003c\/h4\u003e\u003cp\u003eELISA, WB, IP\u003c\/p\u003e\u003ch4\u003eRecommended dilution\u003c\/h4\u003e\u003cp\u003eWB: 1:500-1:3000; IP: 1:500-1:1000\u003c\/p\u003e\u003ch4\u003eGene ID\u003c\/h4\u003e\u003cp\u003e340419\u003c\/p\u003e\u003ch4\u003eResearch Area\u003c\/h4\u003e\u003cp\u003eNeuroscience, Cardiovascular\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100µg \/ Rabbit \/ Q6UXX9","offer_id":42542023213290,"sku":"ABCF07349","price":260.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_2d484b7c-e8a1-4fb8-a03b-ca3d8517490f.png?v=1646164319","url":"https:\/\/danabiosci.com\/products\/anti-rspo2-antibody-abcf07349","provider":"Dana Bioscience","version":"1.0","type":"link"}