{"product_id":"anti-raidd-antibody-abcf06937","title":"anti- RAIDD antibody","description":"\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eUniprot ID\u003c\/h4\u003e\u003cp\u003eP78560\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eliquid\u003c\/p\u003e\u003ch4\u003ePurification\u003c\/h4\u003e\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\u003ch4\u003ePurity\u003c\/h4\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e\n\u0026gt;= 95%\u003c\/p\u003e as determined by SDS-PAGE\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003epolyclonal\u003c\/p\u003e\u003ch4\u003eClone ID\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eStorage\u003c\/h4\u003e\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eRAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL\/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses.\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eCASP2 and RIPK1 domain containing adaptor with death domain\u003c\/p\u003e\u003ch4\u003eSynonyms\u003c\/h4\u003e\u003cp\u003eCRADD, RAIDD\u003c\/p\u003e\u003ch4\u003eObserved MW\u003c\/h4\u003e\u003cp\u003e23 kDa\u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Mouse, Rat\u003c\/p\u003e\u003ch4\u003eTested Application\u003c\/h4\u003e\u003cp\u003eELISA, WB, IHC, IP\u003c\/p\u003e\u003ch4\u003eRecommended dilution\u003c\/h4\u003e\u003cp\u003eWB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200\u003c\/p\u003e\u003ch4\u003eGene ID\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eResearch Area\u003c\/h4\u003e\u003cp\u003eSignal Transduction, Metabolism\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100µg \/ Rabbit \/ P78560","offer_id":42542003257578,"sku":"ABCF06937","price":240.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_a551f210-c894-42c6-8499-569d35143c7c.png?v=1646163737","url":"https:\/\/danabiosci.com\/products\/anti-raidd-antibody-abcf06937","provider":"Dana Bioscience","version":"1.0","type":"link"}