{"product_id":"anti-pick1-antibody-abcf06295","title":"anti- PICK1 antibody","description":"\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eUniprot ID\u003c\/h4\u003e\u003cp\u003eQ9NRD5\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eliquid\u003c\/p\u003e\u003ch4\u003ePurification\u003c\/h4\u003e\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\u003ch4\u003ePurity\u003c\/h4\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e\n\u0026gt;= 95%\u003c\/p\u003e as determined by SDS-PAGE\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003epolyclonal\u003c\/p\u003e\u003ch4\u003eClone ID\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eStorage\u003c\/h4\u003e\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eProbable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1\/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2\/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor(AMPAR) endocytosis. Via interaction with the Arp2\/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression(LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2\/3 complex activator WASL\/N-WASP function.\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eprotein interacting with PRKCA 1\u003c\/p\u003e\u003ch4\u003eSynonyms\u003c\/h4\u003e\u003cp\u003ePRKCABP\u003c\/p\u003e\u003ch4\u003eObserved MW\u003c\/h4\u003e\u003cp\u003e50-55 kDa\u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Mouse, Rat\u003c\/p\u003e\u003ch4\u003eTested Application\u003c\/h4\u003e\u003cp\u003eELISA, IHC, WB, IP, IF\u003c\/p\u003e\u003ch4\u003eRecommended dilution\u003c\/h4\u003e\u003cp\u003eWB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200\u003c\/p\u003e\u003ch4\u003eGene ID\u003c\/h4\u003e\u003cp\u003e9463\u003c\/p\u003e\u003ch4\u003eResearch Area\u003c\/h4\u003e\u003cp\u003eNeuroscience, Signal Transduction\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100µg \/ Rabbit \/ Q9NRD5","offer_id":42541977108714,"sku":"ABCF06295","price":240.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_392e6df1-25c2-4917-80ad-6ee6323be4b7.png?v=1646162784","url":"https:\/\/danabiosci.com\/products\/anti-pick1-antibody-abcf06295","provider":"Dana Bioscience","version":"1.0","type":"link"}