{"product_id":"anti-nf2-antibody-abcf05561","title":"anti- NF2 antibody","description":"\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eUniprot ID\u003c\/h4\u003e\u003cp\u003eP35240\u003c\/p\u003e\u003ch4\u003eForm\u003c\/h4\u003e\u003cp\u003eliquid\u003c\/p\u003e\u003ch4\u003ePurification\u003c\/h4\u003e\u003cp\u003eImmunogen affinity purified\u003c\/p\u003e\u003ch4\u003ePurity\u003c\/h4\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e\n\u0026gt;= 95%\u003c\/p\u003e as determined by SDS-PAGE\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003epolyclonal\u003c\/p\u003e\u003ch4\u003eClone ID\u003c\/h4\u003e\u003cp\u003e\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eStorage\u003c\/h4\u003e\u003cp\u003ePBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze \/ thaw cycles.)\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eProbable regulator of the Hippo\/SWH(Sav\/Wts\/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo\/SWH(Sav\/Wts\/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP\/DCAF1 E3 ubiquitin-protein ligase complex.\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eneurofibromin 2(merlin)\u003c\/p\u003e\u003ch4\u003eSynonyms\u003c\/h4\u003e\u003cp\u003eSCH\u003c\/p\u003e\u003ch4\u003eObserved MW\u003c\/h4\u003e\u003cp\u003e66-70 kDa \u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman, Mouse, Rat\u003c\/p\u003e\u003ch4\u003eTested Application\u003c\/h4\u003e\u003cp\u003eELISA, WB\u003c\/p\u003e\u003ch4\u003eRecommended dilution\u003c\/h4\u003e\u003cp\u003eWB: 1:500-1:2000\u003c\/p\u003e\u003ch4\u003eGene ID\u003c\/h4\u003e\u003cp\u003e4771\u003c\/p\u003e\u003ch4\u003eResearch Area\u003c\/h4\u003e\u003cp\u003eStem Cells\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100µg \/ Rabbit \/ P35240","offer_id":42541946077418,"sku":"ABCF05561","price":240.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_ad11b27b-fcac-4bf0-b1c3-2b8e87bc67fe.png?v=1646161657","url":"https:\/\/danabiosci.com\/products\/anti-nf2-antibody-abcf05561","provider":"Dana Bioscience","version":"1.0","type":"link"}