{"product_id":"abbkine-prp1217-1mg","title":"Human 4-1BBL Protein, His tag (Animal-Free)","description":"\u003cp\u003e\u003cstrong\u003ePrimary Product Type:\u003c\/strong\u003e Cytokines and proteins\u003c\/p\u003e\u003cp\u003e4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation.Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.\u003c\/p\u003e","brand":"Abbkine","offers":[{"title":"1 mg","offer_id":51542017736984,"sku":"PRP1217-1mg","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/abbkine-logo-1_c55ddc15-c7ee-4a1a-ab02-bed0c7f3b95b.png?v=1768035132","url":"https:\/\/danabiosci.com\/products\/abbkine-prp1217-1mg","provider":"Dana Bioscience","version":"1.0","type":"link"}