{"product_id":"abbkine-prp1177-100g","title":"Mouse IL-38 Protein, His tag (Animal-Free)","description":"\u003cp\u003e\u003cstrong\u003ePrimary Product Type:\u003c\/strong\u003e Cytokines and proteins\u003c\/p\u003e\u003cp\u003eInterleukin 38 (IL-38) is a 16.87 kDa cytokine with 152 amino acid residues and a member of the interleukin-1 (IL-1) family. IL-38 is primarily secreted from basal epithelia of the skin and B cells of the tonsil, spleen, and thymus. It plays essential roles in inflammation and host defense by mediating NF-κB, AP1, and JNK signaling pathways when IL-38 binds to the receptors like IL1RAPL1 and IL-36R. In addition, IL-38 participates in down-regulating cell proliferation, migration, and up-regulating IL-6 and IL-10.\u003c\/p\u003e","brand":"Abbkine","offers":[{"title":"100 μg","offer_id":51541600174360,"sku":"PRP1177-100g","price":619.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/abbkine-logo-1_ebaf4e6e-a679-441d-83e7-370a4dbb62ad.png?v=1768026895","url":"https:\/\/danabiosci.com\/products\/abbkine-prp1177-100g","provider":"Dana Bioscience","version":"1.0","type":"link"}