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ADC Linker Performance: Payload Release, Liver ...

ADC Linker Performance: Payload Release, Liver Lysosome Catabolism, and Lysosomal Stability Mediated by Cathepsin B in DS8201a and GGFG-DxD Systems Keywords: ADC linker, Payload release, liver lysosome, lysosomal stability, lysosome...

N-Nitrosamines: An Enhanced Ames Test with Hams...

N-Nitrosamines: An Enhanced Ames Test with Hamster liver S9 Keywords: N-Nitrosamines, NDSRIs, OECD 471, Enhanced Ames test, Hamster liver S9, Cytochrome P450 enzymes, Mutation Test IPHASE Products Product Name  Specification...

[KO Validated] CDKN1A/p21 Rabbit mAb

The p53-p21-RB axis regulates the transcription of numerous genes critical for cell cycle control. p53 activation induces p21/CDKN1A, which inhibits cyclin-CDK complexes, leading to RB hypophosphorylation and repression of E2F-dependent...

2025 CUSABIO Monthly Citation Review

2025 CUSABIO Monthly Citation Review Top 1 Article Title: Neurotensin-neurotensin receptor 2 signaling in adipocytes suppresses food intake through regulating ceramide metabolism Journal Name: Cell Research Impact Factor: 28.4 CUSABIO Citation Product: Mouse...

Engineered Patelets as Targeted Protein Degrade...

Engineered Patelets as Targeted Protein Degraders and Application to Breast Cancer Models   ●Publication Date: 03 December 2024 ●Journal: Nature Biotechnology ●Impact Factor: 33.1 ●DOI: 10.1038/s41587-024-02494-8 Keywords Engineered platelets Heat shock protein 90 (HSP90) Breast...

Discover CUSABIO's Cancer Research Solutions

Cancer is the second leading cause of death globally. However, with continuous advancements in science and technology, the survival rates for many types of cancer are gradually improving. We have...