Research Grade Biosimilar Antibodies, also known as recombinant reference monoclonal antibodies (rmAb), are valuable tools for researchers working in immuno-oncology, targeted oncology, autoimmune disease, inflammation, infectious disease, complement biology, respiratory disease, and therapeutic antibody research.
AntibodySystem provides a broad portfolio of research-grade biosimilar antibodies that are recombinant, sequence-defined, and produced in mammalian cells for excellent lot-to-lot consistency. These antibodies are designed for research use as positive controls, reference standards, assay calibrators, neutralization tools, and method-development reagents.
What Are Research Grade Biosimilar Antibodies?
Research grade biosimilar antibodies are non-clinical, research-use-only versions of well-known therapeutic and clinical-stage antibody clones. They are not intended for therapeutic, diagnostic, or clinical use, but they provide researchers with reliable antibody references for in vitro assay development and validation.
Because these antibodies are sequence-defined and recombinantly expressed, they offer consistent performance across batches. This makes them useful for laboratories developing ELISA, SPR, flow cytometry, Fc receptor binding, neutralization, and blocking assays.
Therapeutic Areas Covered
- Immuno-oncology
- Targeted oncology
- Autoimmune and inflammatory disease
- Complement and rare disease research
- Allergy and respiratory disease
- Infectious disease
- Veterinary research
AntibodySystem rmAb Portfolio at a Glance
- 3,500+ clones: Broad collection of research-grade biosimilar antibodies
- Recombinant production: Mammalian cell expression for lot-to-lot consistency
- >95% purity: Confirmed by SDS-PAGE
- Protein A/G purified: Suitable for assay and method development
- Multi-format: IgG, Fc-fusion proteins, bispecific antibodies, and VHH/nanobodies
Key Specifications
| Specification | Description |
|---|---|
| Clonality | Recombinant monoclonal |
| Expression | Mammalian cells |
| Purity | >95% by SDS-PAGE |
| Purification | Protein A/G |
| Host | Human, humanized, chimeric, murine |
| Isotype | IgG1 / IgG2 / IgG4, κ / λ |
| Format | Liquid in PBS, pH 7.4 |
| Grade | Research Use Only (RUO) |
Typical Applications
- Positive controls
- Reference standards
- Assay calibration
- Neutralization and blocking assays
- Fc-receptor studies
- ELISA method development
- SPR method development
- Flow cytometry controls
Why Researchers Use AntibodySystem rmAbs
AntibodySystem rmAbs are designed to support reproducible research. Since they are recombinant and sequence-defined, they provide consistency that is especially important for assay development, lot comparison, screening, and reference-standard workflows.
- Sequence-defined recombinant monoclonal antibodies
- Reference versions of named clinical antibody clones
- Broad target and format coverage
- Human, humanized, chimeric, murine, and veterinary options
- Defined isotype information including IgG1, IgG2, IgG4, κ and λ
- High-purity material supplied in liquid PBS format
- Datasheet available for each catalog number
Featured Research Grade Biosimilar Antibodies
| Catalog No. | Antibody | Target | Isotype | Host |
|---|---|---|---|---|
| DHC09601 | Research Grade Trastuzumab | HER2 | IgG1, κ | Humanized |
| DHC09602 | Research Grade Pertuzumab | HER2 | IgG1, κ | Humanized |
| DHD12602 | Research Grade Bevacizumab | VEGF-A | IgG1, κ | Humanized |
| DHE16601 | Research Grade Ramucirumab | VEGFR2 | IgG1, κ | Human |
| DHB86902 | Research Grade Cetuximab | EGFR | IgG1, κ | Chimeric |
| DHH02202 | Research Grade Pembrolizumab | PD-1 | IgG4, κ | Humanized |
| DHH02209 | Research Grade Nivolumab | PD-1 | IgG4, κ | Human |
| DHJ70101 | Research Grade Atezolizumab | PD-L1 | IgG1, κ | Humanized |
| DHJ70102 | Research Grade Durvalumab | PD-L1 | IgG1, κ | Human |
| DHB94402 | Research Grade Adalimumab | TNF-α | IgG1, κ | Human |
Research Use Only Notice
All AntibodySystem research grade biosimilar antibodies are supplied for Research Use Only (RUO). They are not intended for clinical, therapeutic, diagnostic, or human use.
Request the Full rmAb List
AntibodySystem offers more than 3,500 research-grade biosimilar antibody clones. Contact us for the full product list, datasheets, quotation, and distributor support.