Necroptosis is an uncontrolled cell death process triggered by abnormal environments or injuries,commonly seen in severe tissue damage, ischemia, infection, and inflammatory pathological states.
This type of cell death can be activated by tumor necrosis factor receptor (TNFR), with key proteins including RIPK1, RIPK3, and MLKL. Necroptosis occurs through three stages when cells are subjected to injurious stimuli: the formation of complex I, the formation of complex IIa, and the activation of complex IIb (necrosome), ultimately leading to cell necrosis.
Related Antibodies
|
Target |
Cat.# |
Product Name |
Reactivity |
Application |
|
A20 |
AMRe02701 |
TNFAIP3 Rabbit Monoclonal Antibody |
Human |
WB,IHC,ICC/IF |
|
APRab00097 |
TNFAIP3 Rabbit Polyclonal Antibody |
Human |
WB,IHC,ICC/IF |
|
|
Caspase-8 |
AMRe04140 |
Caspase 8 Rabbit Monoclonal Antibody |
Human,Hamster |
WB |
|
AMM03879 |
Cleaved-Caspase 8 Mouse Monoclonal Antibody |
Human,Mouse,Rat |
WB,IHC,ICC/IF |
|
|
FADD |
AMRe01969 |
FADD Rabbit Monoclonal Antibody |
Human,Mouse |
WB,IHC |
|
APRab00258 |
FADD Rabbit Polyclonal Antibody |
Human |
WB |
|
|
MLKL |
AMRe04148 |
MLKL Rabbit Monoclonal Antibody |
Human,Mouse |
WB |
|
RIPK |
AMRe03794 |
RIP Rabbit Monoclonal Antibody |
Human |
WB |
|
TNFR |
APRab01356 |
TNF Receptor 2 Rabbit Polyclonal Antibody |
Human,Mouse,Rat |
WB,IHC,ICC/IF |
|
TRIF |
AMRe02715 |
TRIF Rabbit Monoclonal Antibody |
Human,Mouse,Rat |
WB |