Mycoplasma contamination is one of the most common problems in cell culture laboratories. Reliable mycoplasma detection is critical for maintaining cell line integrity and ensuring experimental reproducibility.
Why Mycoplasma Is Dangerous
- Alters gene expression
- Changes cell growth behavior
- Interferes with experimental results
Common Detection Methods
- PCR-based mycoplasma detection
- DNA staining methods
- Culture-based assays
PCR-based mycoplasma detection kits are currently the most widely used tools because of their high sensitivity and rapid workflow.