🧬 What is Insulin Resistance (IR)?
Insulin is the only hormone that lowers blood glucose and plays a crucial role in the synthesis of glycogen, fat, and protein.
When cells become less responsive to insulin, this condition is known as Insulin Resistance (IR).
⚠️ Problems Caused by IR
- Hyperglycemia → Leads to Type 2 Diabetes
- Hyperlipidemia → Atherosclerosis, Hypertension, Coronary Heart Disease
- Increased Ketone Bodies → Ketoacidosis
- Primary cause of Metabolic Syndrome
🧪 Relationship Between IR and Adipokines
Insulin resistance is closely associated with obesity and abnormal secretion of adipokines, hormones produced by adipose tissue.
FineTest offers high-quality ELISA kits to support IR-related research.
🔬 Featured ELISA Kits for IR Research
1️⃣ Adiponectin
Regulates glucose and fatty acid metabolism and is negatively correlated with IR.
| Species | Cat.No | Species | Cat.No | Species | Cat.No |
|---|---|---|---|---|---|
| Human | EH2165 | Rat | ER0006 | Porcine | EP0006 |
| Mouse | EM0383 | Rabbit | ERB0002 | Chicken | ECH0002 |
2️⃣ Leptin
Involved in appetite regulation and energy expenditure; positively correlated with IR.
| Species | Cat.No | Species | Cat.No | Species | Cat.No |
|---|---|---|---|---|---|
| Human | EH0216 | Mouse | EM0129 | Porcine | EP0103 |
| Rat | ER0115 | Sheep | ESH0050 | Monkey | EMK0046 |
3️⃣ Resistin
Involved in glucose homeostasis and regulation of insulin resistance.
| Species | Cat.No | Species | Cat.No | Species | Cat.No |
|---|---|---|---|---|---|
| Human | EH0269 | Mouse | EM0168 | Sheep | ESH0040 |
4️⃣ IL-6
Regulates inflammation and immune response; induces IR by inhibiting the IRS-1 pathway.
| Species | Cat.No | Species | Cat.No | Species | Cat.No |
|---|---|---|---|---|---|
| Human | EH0201 | Mouse | EM0121 | Monkey | EMK0041 |
| Guinea Pig | EGP0070 | Rabbit | ERB0068 | Sheep | ESH0019 |
📌 Popular Research Areas
- Cytokines / Hormones / Infectious Disease ELISA Kits
- Autoimmune, Anaphylaxis, Immune Checkpoints
- Monkeypox / Tumor Biomarkers / Antibody Drug ELISAs
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