Disulfidptosis

Disulfidptosis

Disulfidptosis, a novel form of cell death identified in a publication in March 2023, primarily occurs in cells with high expression of SLC7A11. Under conditions of glucose deprivation, these cells experience abnormal accumulation of cystine and other disulfides within the cell, triggering disulfide stress. This leads to an increase in the content of disulfide bonds in the actin cytoskeleton,causing actin filaments to contract and disrupt the cytoskeletal structure, resulting in cell death.The process involves glucose uptake, cystine uptake, and the pentose phosphate pathway.

Product Introduction

Metabolism kits are detection tools developed based on chemical reactions, enzyme-catalyzed reactions,or the characteristics of material structures, specifically designed for the determination of substance content or enzyme activity in samples.

Product Advantages

· Comprehensive Range：Covers a variety of series, including amino acids and proteins, carbohydrate and lipid metabolism, liver and kidney function, oxidative stress, ferroptosis, metabolic diseases,mitochondrial function, inorganic salt ions, energy metabolism, cuproptosis, and disulfidptosis, meeting

diverse detection needs.

· Wide Sample Applicability：Suitable for various sample types, including animal and plant tissues,serum, plasma, cells, bacteria, and multiple body fluids.

· Advanced Detection Technology：Utilizes efficient and innovative detection technologies combined with optimized experimental protocols to ensure the accuracy and reproducibility of the results.

· Complete Accessories: The kits include all reagents and standards required for detection, along with detailed experimental instructions, making operations more convenient and time-efficient.

· Excellent Performance: High sensitivity, easy operation, and stable performance provide reliableassurance for experiments.