Reliable cryopreservation is a critical step in modern cell culture, biobanking, cell therapy research and translational workflows. For sensitive samples such as PBMCs, T cells, NK cells, CAR-T cells, MSCs, iPSCs and organoids, freezing and thawing conditions can directly affect post-thaw viability, cell recovery, phenotype stability and downstream function.
CellStore Cryopreservation Media, available from Dana Bioscience, are ready-to-use formulations designed for cell type-specific cryopreservation. The portfolio includes both DMSO-based and DMSO-free media for immune cells, stem cells, cell lines, tissues and organoids.
Why Cryopreservation Media Selection Matters
Conventional freezing workflows may expose cells to ice crystal damage, osmotic stress, DMSO toxicity and thawing-related stress. These factors can reduce cell viability, lower recovery rates, alter immune cell subset distribution and affect downstream assays such as flow cytometry, proliferation analysis and cytotoxicity testing.
CellStore approaches this challenge through Ice-controlling Technology, a platform designed to regulate ice crystal nucleation, size, morphology and growth. By helping control the freezing microenvironment, CellStore media aim to improve post-thaw consistency across advanced cell culture workflows.
Application-Focused Product Portfolio
1. PBMC and Whole Blood Workflows
CS-PM-D1 PBMC Cryopreservation Medium is designed for whole blood, leukopak, PBMC, CBMC and buffy coat cryopreservation. CellStore data show high post-thaw viability and viable cell recovery, with immune subset distribution comparable to fresh samples in PBMC studies.
2. Immune Cell Cryopreservation
CS-AT-D2 Immune Cell Cryopreservation Medium is intended for immune cell types such as CAR-T, UCAR-T, NK, CAR-NK, αβ-T and γδ-T cells. The supplied data include post-thaw viability, recovery and functional evaluation for T cells, NK cells and CAR-T workflows.
3. Stem Cell Cryopreservation
CellStore offers DMSO-free and DMSO-based cryopreservation media for MSCs, iPSCs, cord blood stem cells and neural precursor stem cells. These products are suitable for stem cell culture, regenerative medicine research and process development applications.
4. Cell Line Cryopreservation
CellStore cell line cryopreservation media are designed for commonly used research cell lines including CHO, HEK293, 293T, hybridoma, Jurkat and related cell culture models. DMSO-free options are also available for selected research workflows.
5. Tissue and Organoid Preservation
The tissue and organoid product line includes tissue preservation medium, tissue cryopreservation medium and organoid cryopreservation medium. These solutions are intended to support laboratories working with organoid models, tissue-derived samples and advanced 3D culture systems.
Quality and Documentation
CellStore documentation describes GMP-compliant production, quality control testing, ISO certifications and regulatory documentation for selected products, including FDA DMF and NMPA pharmaceutical excipient filings. Available technical materials include performance data, product specifications and application-focused validation data.
Recommended Use Cases
- PBMC and leukopak banking
- CAR-T, NK and T cell process development
- Stem cell and regenerative medicine research
- Cell line storage and routine cell culture workflows
- Tissue and organoid cryopreservation
- Decentralized sample collection followed by centralized analysis
CellStore Products from Dana Bioscience
Dana Bioscience supplies CellStore cryopreservation media for research laboratories, biotech companies and translational research teams looking for specialized cryopreservation solutions. Contact Dana Bioscience for product selection support, pricing, technical documents, sample evaluation or bulk supply inquiries.
For research use or process development use only unless otherwise stated in official product documentation.