Identify rare tumor TCR biomarkers and biological insights with ultrasensitive chemistry
Accurate analysis of mouse T-cell receptor (TCR) repertoires is critical for studying T-lymphocyte biology, immune dynamics in aging, and TCR biomarkers for the development of cancer vaccines or therapies. While most library preparation tools struggle to identify rare T cells or work with low RNA input, SMART-Seq Mouse TCR (with UMIs) generates reproducible libraries that faithfully reflect the full range of T-cell diversity, including rare populations, in your samples.
The kit empowers you to uncover more insights from your samples than ever before with features like:
- Compatibility with a wide range of sample inputs—produce data from inputs as low as >1 ng of total RNA from mouse spleen or T cells; >10 ng of total RNA obtained from mouse whole blood, bone marrow, or thymus; or >100 purified mouse T cells
- Accurate UMI-based correction—control for PCR bias and correct artifacts in your NGS libraries
- Versatile sequencing options—choose to sequence either the full-length V(D)J or only the CDR3 region, depending on your needs and budget
- Streamlined workflow—save time and money by pooling up to 384 samples with UDIs and using total RNA from lymphoid tissue without extra sorting/enrichment steps
| Cat. # | Product | Size | ||
|---|---|---|---|---|
| 634816 | SMART-Seq Mouse TCR (with UMIs) | 96 Rxns |